Juan Garcia Vallejo
MD, PhD, MBA
Keywords: Glioblastoma, immune monitoring, infections, exposure to microplastics
Technologies
(imaging) mass cytometry
spectral flow cytometry
unsupervised data analysis
Tanja de Gruijl
PhD
Keywords: Immune monitoring, dendritic cells, tumor-draining lymph nodes, oncolytic viruses, bispecific T-cell engagers
Technologies
flow cytometry
T-cell cultures
viral transduction
cytotoxicity assays
(3D) tumor cultures
Idris Bahce
MD, PhD
Keywords: NSCLC, immunotherapy, radiotherapy, surgery, immuno-PET
Technologies
(imaging) mass cytometry
flow cytometry
PET scan
Yvette van Kooyk
PhD
Keywords: TME, glycosylation, cancer vaccines, dendritic cells, macrophages
Technologies
flow cytometry
microscopy
animal models
CRISPR/Cas9
Sarah Derks
MD, PhD
Keywords: gastroesophageal cancer, immune exclusion
Technologies
spatial transcriptomics
flow cytometry
multicolor immunohistochemestry
Filip Eftimov
MD, PhD
Keywords: CIDP, Myositis, Myasthenia, Neuroimmunology, Vaccine Responses
Technologies
clinical cohorts
cytometry
proteomics
Adriaan Bins
MD, PhD
Keywords: Renal Cell Carcinoma, Immuno-Oncology, Vaccination
Technologies
clinical cohorts
NGS
elispot
biobanking
Febe van Maldegem
PhD
Keywords: NSCLC, immunotherapy, radiotherapy, image analysis
Technologies
imaging mass cytometry
mouse models
patient tissues analysis
tumour/cell cultures
immunofluorescence
Arjan Griffioen
MD, PhD
Keywords: Angiogenesis, tumor vasculature, endothelium, immunotherapy, vaccination
Technologies
recombinant vaccine production
in vitro and in vivo angiogenesis assays
immune profiling
mouse cancer models
Rieneke van de Ven
PhD
Keywords: head and neck squamous cell carcinoma, tumor immune microenvironment, immune suppression, biomarker identification, immunotherapy
Technologies
flow cytometry
fluorescent multiplex immunohistochemistry
transwell migration assays
functional T cell assays
Maarten Bijlsma
MD, PhD
Keywords: stroma, esophageal cancer, pancreatic cancer, therapy resistance, drug repurposing
Technologies
lineage tracing
CRISPR/Cas-9
next-generation sequencing
metabolomic
animal models
Monika Wolkers
PhD
Keywords: Translation regulation in immune cells, molecular T cell biology, cancer immunology
Technologies
flow cytometry
cell culture
RNA analysis
proteomics
RNA-protein interactions
Jan Van den Bossche
PhD
Keywords: immunometabolism, macrophage, innate immunity, atherosclerosis, cancer
Technologies
Spectral and flow cytometry
Agilent Seahorse metabolic flux analysis
Biotek Cytation imaging and multimode reading
(single-cell) immunometabolic profiling
Marieke Fransen
PhD
Keywords: Immunotherapy, NSCLC, lymph nodes, Tumor Microenvironment
Technologies
Flowcytometry
Cell culture
ELISA
Victor van Beusechem
PhD
Keywords: cancer immunotherapy, oncolytic virus, gene therapy, RNA interference
Technologies
genetic engineering
high-throughput screening
CAM tumor models
multiplexed immunofluorescence assays
Sandra van der Vliet
PhD
Keywords: Glycosylation, colorectal cancer, dendritic cells, anti-tumor immunity
Technologies
Flow cytometry
CRISPR/Cas9
immune-tumor co-cultures
glycan analysis
Arnon Kater
MD, PhD
Keywords: tumor microenvironment, immunometabolism, T cell differentiation, multispecific T cell engagers, CAR-T
Technologies
Flowcytometry
metabolic measurements
various ‘omics’
Maria Themeli
PhD
Keywords: chimeric antigen receptor, adoptive cell immunotherapy, genetic engineering, induced pluripotent stem cells
Technologies
Chimeric Antigen Receptors (CARs)
genetic engineering of T cells
gene editing
induced Pluripotent Stem Cells
in vivo models
Rosalie Luiten
PhD
Keywords: autoimmunity, cancer immunity, skin diseases, immunotherapy, biomarkers
Technologies
Flow Cytometry
immune monitoring of patients
human T cell culture and activation assays
multiplex immunohistochemistry (Vectra Polaris)
human skin explants
murine skin cancer models (melanoma and BCC)
bioinformatics
Hanneke van Laarhoven
MD, PhD
Keywords: gastric cancer, esophageal cancer, biobank
Technologies
Flow cytometry
RNA seq
organoid cultures
Richard Groen
PhD
Keywords: Multiple Myeloma, CAR T cell, therapy resistance, hematological PDX models
Technologies
3D bone marrow (perfusion) cultures
induced pluripotent stem cells
flow cytometry
bioluminescent imaging
PDX mouse models for hematology
Danielle Vugts
PhD
Keywords: Positron emission tomography (PET), Radiolabeling, drug development
Technologies
PET
Conny van der Laken
PhD
Keywords: Molecular imaging, rheumatic autoimmune diseases, immunotherapy related side effects
Technologies
Flow Cytometry
immunohistochemistry
molecular imaging
Willemien Menke-van der Houven van Oordt
MD, PhD
Keywords: PET imaging; drug development; breast cancer; phase 1 clinical trials; immunotherapy
Technologies
PET
Immunomonitoring (multiplex, FACS ao) of tumor/blood samples
Immunotherapy Center 